Plans to upgrade the UK's aviation network and stimulate the country's international trade links have been criticised for what is described as a lack of long-term vision.
Transport for London (TfL) has described the independent Airports Commission's report - delivered last month - as placing more weight on "accommodating short-term commercial interests".
The Commission has put forward suggestions for boosting capacity at the terminals of the UK's airports by building a new runway at either Heathrow or Gatwick.
But both plans would result in hundreds of houses being destroyed, and cherished buildings being razed, as developers sought to accommodate the investment.
London mayor Boris Johnson has made no secret of his preferred option, which is for a new airport in the Thames estuary, off the Isle of Grain. It has been dubbed Boris Island.
TfL says neither option recommended in the Airports Commission's report would address the real need for a long-term solution.
In its response, published online today, TfL said: " The interim report and the recently published appraisal criteria places more weight on accommodating short-term commercial interests, than a strategic vision for aviation which is able to secure the UK's long term economic prosperity.
"The commission identify a significant capacity gap in 2050, but do not address this. They focus instead on runway capacity options to 2030.
"This does not provide the UK with a long term plan. Their approach also places inadequate weight on public health and quality of life, including air-quality impacts, which are not considered in any detail."
Options floated by the commission include the creation of a third runway at Heathrow, or extending the northern runway to the west. Both would cause at least 750 homes to be demolished .
But TfL believes the extra runway would have swallowed all potential for growth by 2030, meaning domestic destinations would be "traded off against lucrative long-haul routes", it said. Only a new four-runway hub could address this issue properly, TfL says.
TfL says the primary capacity issue is with Heathrow, something it accuses the commission of ignoring.
It also criticises the commission's Heathrow plans for "eroding" windows of "respite" for those near the flight path from noise pollution, as well as questioning whether attention is paid to long-term transport infrastructure connecting mainline rail service with international destinations.
The TfL report adds: "Some of the conclusions are inconsistent and incorrect, and in a number of instances the findings of the technical work it (the commission) has commissioned have been diluted."
An Airports Commission spokesman said: "Decisions about airport capacity are of vital national importance and must be based on the best evidence available. The commission is undertaking a thorough, comprehensive and transparent study subject to rigorous assessment considering economic, social and environmental impacts.
"This work will continue to develop as comprehensive a picture as possible of the risks and opportunities of each option identified. This will be followed by a full consultation later this year on the design and appraisal of each option."